New MRI technique could spot brain tumor markers without a scalpel
NCT ID NCT03684109
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study is testing whether a special MRI scan can measure a substance called 2-hydroxyglutarate (2HG) in brain tumors (gliomas) without needing surgery. Researchers will compare the MRI results with measurements from actual tumor tissue removed during surgery. If the MRI method works, it could help doctors diagnose and track gliomas more easily and guide the development of new treatments. The study involves 30 adults with suspected or confirmed gliomas who are already scheduled for a biopsy or tumor removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive way to measure a key brain tumor marker, helping doctors diagnose and monitor gliomas without surgery.
- What could go wrong
- This is a very early pilot study with only 30 participants. The MRI technique may not be accurate enough to replace tissue samples, and results may not apply to all glioma patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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