New drug shows promise in hitting Hard-to-Treat brain cancers

NCT ID NCT05076513

First seen Mar 15, 2026 · Last updated May 14, 2026 · Updated 8 times

Summary

This study tests a drug called niraparib in people with two types of brain tumors: newly diagnosed glioblastoma and recurrent IDH-mutant glioma with ATRX loss. The goal is to see if the drug reaches the tumor and slows its growth. Up to 42 participants will receive niraparib before and after surgery, with some also getting standard radiation. The trial is in an early phase, so it focuses on safety and how the drug works in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • St. Joseph's Hospital and Medical Center

    Phoenix, Arizona, 85013, United States

Conditions

Explore the condition pages connected to this study.