New obesity drug combo shows promise in Mid-Stage trial

NCT ID NCT06577090

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new injectable drug called nimacimab, given weekly, to see if it helps overweight or obese adults lose weight. Some participants will receive nimacimab alone, others will get it together with semaglutide (a known weight-loss drug), and some will receive a placebo. The trial involves 136 people and aims to measure changes in body weight and waist size over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ACCEL Research Sites

    Atlanta, Georgia, 30342, United States

  • Accellacare of Wilmington

    Wilmington, North Carolina, 28401, United States

  • ActivMed Practices & Research

    Portsmouth, New Hampshire, 03801, United States

  • Be Well Clinical Studies

    Lincoln, Nebraska, 68516, United States

  • Be Well Clinical Studies

    Round Rock, Texas, 78681, United States

  • Center for Advanced Research & Education

    Gainesville, Georgia, 30501, United States

  • Charlottesville Medical Research

    Charlottesville, Virginia, 22911, United States

  • Chase Medical Research, LLC

    Waterbury, Connecticut, 06708, United States

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Lillestol Research, LLC

    Fargo, North Dakota, 58104, United States

  • Palm Research Center

    Las Vegas, Nevada, 89148, United States

  • Pinnacle Research Group

    Anniston, Alabama, 36207, United States

  • Rainier Clinical Research Center

    Renton, Washington, 98057, United States

  • Velocity Clinical Research, Dallas

    Dallas, Texas, 75230, United States

  • Weill Cornell Medicine

    New York, New York, 11375, United States