New catheter aims to tame stubborn AFib

NCT ID NCT07321002

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new shape-adaptive catheter that uses pulsed field ablation to treat persistent atrial fibrillation (AFib), a type of irregular heartbeat. 35 adults with persistent AFib will receive the procedure under general anesthesia. Researchers will check for serious side effects within 7 days and see if the treatment successfully restores normal heart rhythm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PFLotus catheter and DePolar mapping system
What this could lead to
If successful, this could provide a safer and more effective way to treat persistent atrial fibrillation using a single catheter system.
What could go wrong
This is a small, early-stage trial with only 35 participants. The procedure carries risks like bleeding, heart damage, or irregular heartbeat. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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