New catheter aims to tame stubborn AFib

NCT ID NCT07321002

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new shape-adaptive catheter that uses pulsed field ablation to treat persistent atrial fibrillation (AFib), a type of irregular heartbeat. 35 adults with persistent AFib will receive the procedure under general anesthesia. Researchers will check for serious side effects within 7 days and see if the treatment successfully restores normal heart rhythm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PFLotus catheter and DePolar mapping system

What this could lead to

If successful, this could provide a safer and more effective way to treat persistent atrial fibrillation using a single catheter system.

What could go wrong

This is a small, early-stage trial with only 35 participants. The procedure carries risks like bleeding, heart damage, or irregular heartbeat. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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