Sound waves instead of needles: new device targets back pain without piercing skin
NCT ID NCT07647757
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether a device called Neurolyser XR can safely ease low back pain caused by sacroiliitis (inflammation of the joint at the base of the spine). The device uses high-intensity focused ultrasound to block pain signals from the joint, without needles or cutting the skin. About 30 adults with long-term sacroiliac joint pain will receive the treatment, and researchers will measure changes in pain levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
high intensity focused ultrasound (Neurolyser XR device)
What this could lead to
If it works, this could offer a needle-free, low-discomfort option for people with chronic low back pain from sacroiliitis.
What could go wrong
This is a small, early-stage study with only 30 participants. The device may not provide lasting pain relief, and risks like unintended tissue damage are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Neuroscience, Reproductive and Odontostomatological Sciences
Naples, 80131, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••