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Double nerve block may ease pain and speed recovery after heart surgery

NCT ID NCT07716943

Symptom relief Sponsor: Sisli Hamidiye Etfal Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether combining two ultrasound-guided nerve blocks—the anterior serratus plane block and the pectoral-intercostal plane block—can improve pain control and recovery in adults undergoing open-heart surgery through a chest incision. Participants receive one of the blocks or both before surgery begins. The goal is to see if the combination reduces pain, lowers the need for opioid painkillers, and helps patients leave the hospital sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Combined anterior serratus plane block and pectoral-intercostal plane block
What this could lead to
If effective, this combination of nerve blocks could become a standard way to manage pain after heart surgery, reducing opioid use and helping patients recover faster.
What could go wrong
This is a small, single-center study, so results may not apply to all heart surgery patients. The blocks may not provide enough pain relief or could have rare side effects like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing open heart surgery via median sternotomy by the Cardiovascular Surgery Clinic * Patients over 18 years of age * ASA II-III patients Exclusion Criteria: * \- Patients undergoing emergency or recurrent surgery * Patients with left ventricular ejection fraction \< 30 * Patients who died per-operatively * Patients who do not provide informed consent * Presence of chronic pain * Presence of allergy to local anesthetics * Presence of infection in the area where the block will be performed * Coagulopathy * Pre-existing neurological deficit * Mental retardation * Anatomical deformity

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac surgery Cardiopulmonary bypass Median sternotomy Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Sisli etfal research and training hospital

    Istanbul, 34371, Turkey (Türkiye)

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