Nerve block shots could ease chronic headaches, trial shows
NCT ID NCT07497646
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether repeated injections of a numbing drug (bupivacaine) into the back of the head could help people with chronic migraine or chronic tension-type headache. 290 adults received either the drug or a placebo (salt water) injection over three months. The main goal was to see if the treatment reduced the number of headache days per month.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine (a numbing medication)
What this could lead to
If it works, this could offer a non-daily treatment option to reduce headache frequency and pain for people with chronic migraine or tension-type headache.
What could go wrong
This is a completed trial, but results may not apply to everyone. The effect may be modest, and injections carry risks like pain, bleeding, or infection at the site.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sultan Abdulhamid Han Research and Training Hospital
Istanbul, Istanbul, Turkey (Türkiye)