Smarter breathing machine may help sick babies breathe easier

NCT ID NCT06053684

Recruiting now Symptom relief Sponsor: Montefiore Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two types of non-invasive breathing support for infants under 2 years old with bronchiolitis in the pediatric ICU. One method uses standard ventilation, while the other uses a smarter mode called NAVA that synchronizes with the baby's own breathing. The goal is to see if NAVA improves comfort and reduces the need for a breathing tube.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neurally-Adjusted Ventilatory Assistance (NAVA) non-invasive ventilation
What this could lead to: If it works, this could lead to a more comfortable breathing support method for infants with bronchiolitis, potentially reducing the need for more invasive procedures like intubation.
What could go wrong: This is a relatively small, early-stage trial (130 participants) comparing two ventilation modes, so results may not apply to all patients. The improvement in comfort may not translate to major clinical benefits.

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Conditions

The condition(s) this trial relates to.

bronchiolitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIOLITIS

Contacts and locations

Locations

Children's Hospital at Montefiore
RECRUITING

The Bronx, New York, 10467, United States

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