Nose cells could fix your knee: new implant trial launches
NCT ID NCT06163573
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial tests whether an implant made from a patient's own nasal cartilage can treat patellofemoral osteoarthritis (knee arthritis) better than standard platelet-rich plasma injections. 75 adults aged 18–65 with moderate knee arthritis will be randomly assigned to receive either the implant or injections. The main goal is to see if the implant improves knee pain and function over 24 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nasal cartilage implant (autologous nasal chondrocyte tissue-engineered cartilage graft)
What this could lead to
If successful, this could offer a new, longer-lasting treatment option for knee osteoarthritis that uses the patient's own nasal cells to repair damaged cartilage.
What could go wrong
This is an early phase II trial with only 75 people, so results may not apply to everyone. The implant requires surgery, and there is a risk of side effects or the graft not working as hoped.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Crossklinik
RECRUITINGBasel, 4054, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpitaux universitaires de Genève
RECRUITINGGeneva, 1205, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orthopädische Klinik König-Ludwig-Haus
NOT_YET_RECRUITINGWürzburg, 97074, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale Regionale di Lugano
RECRUITINGLugano, 6962, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Poliklinika Ivković
RECRUITINGZagreb, 10000, Croatia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Poliklinika Ortho Plus
RECRUITINGZagreb, 10000, Croatia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sportclinic, Klinik Hirslanden
RECRUITINGZurich, 8032, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Basel
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsklinikum Freiburg
NOT_YET_RECRUITINGFreiburg im Breisgau, 79106, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••