New pill aims to silence stubborn chronic cough

NCT ID NCT07671924

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new extended-release tablet called nalbuphine for people with refractory chronic cough—a cough that persists despite treatment. About 100 adults will receive either the drug or a placebo for 6 weeks. The main goal is to see if the drug reduces how often people cough over 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nalbuphine extended-release tablets

What this could lead to

If successful, this could provide a new treatment option for people with chronic cough that doesn't respond to other therapies.

What could go wrong

This is an early Phase 2 trial with only 100 participants, so results may not be conclusive. The drug may not reduce cough better than placebo, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Cough

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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  • Contact

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