Trevi Therapeutics
Clinical trials sponsored by Trevi Therapeutics, explained in plain language.
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New pill aims to silence stubborn chronic cough
Symptom relief Recruiting nowThis study tests a new extended-release tablet called nalbuphine for people with refractory chronic cough—a cough that persists despite treatment. About 100 adults will receive either the drug or a placebo for 6 weeks. The main goal is to see if the drug reduces how often people …
Phase: PHASE2 • Sponsor: Trevi Therapeutics • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Could a painkiller stop the cough that Won't quit in lung fibrosis?
Symptom relief Recruiting nowThis study tests whether an extended-release form of nalbuphine, a pain medication, can safely reduce chronic coughing in people with idiopathic pulmonary fibrosis (IPF), a lung scarring disease. About 306 adults with IPF and a cough lasting at least 8 weeks will receive either t…
Phase: PHASE3 • Sponsor: Trevi Therapeutics • Aim: Symptom relief
Last updated Jul 12, 2026 00:00 UTC
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Does breakfast change how this pain drug works? new study investigates
Knowledge-focused Recruiting nowThis early-stage trial is testing whether eating a high-fat, high-calorie meal changes how the body absorbs nalbuphine extended-release tablets. Sixty healthy volunteers will take the drug once with food and once without, and researchers will compare drug levels in their blood. T…
Phase: PHASE1 • Sponsor: Trevi Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC