Trevi Therapeutics

This study tested a new tablet called nalbuphine ER for people with a long-lasting cough that doesn't get better with treatment. 66 adults with refractory chronic cough took the drug or a placebo to see if it reduced coughing. The goal was to measure cough frequency and check for…

This study looked at how a long-acting painkiller (nalbuphine ER) interacts with two lung fibrosis drugs (pirfenidone and nintedanib) in 132 healthy adults. Researchers measured drug levels in the blood and checked for side effects. The goal was to see if these drugs can be safel…

This early-phase study looked at how the drug nalbuphine extended-release is processed in people with mild, moderate, or severe liver problems compared to those with healthy livers. It also explored whether the drug could help relieve itching in participants who reported it. The …