Liver function may affect how itch drug works in body

NCT ID NCT04020016

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study looked at how the body breaks down nalbuphine extended-release tablets in people with mild, moderate, or severe liver impairment compared to healthy volunteers. It also explored whether the drug could relieve itching in those with liver problems. The study involved 28 participants and focused on safety and drug levels in the blood.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 01

    Miami, Florida, 33136, United States

  • 02

    Miami, Florida, 33146, United States

  • 03

    Orlando, Florida, 32809, United States