Liver function may affect how itch drug works in body
NCT ID NCT04020016
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study looked at how the body breaks down nalbuphine extended-release tablets in people with mild, moderate, or severe liver impairment compared to healthy volunteers. It also explored whether the drug could relieve itching in those with liver problems. The study involved 28 participants and focused on safety and drug levels in the blood.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEPATIC IMPAIRMENT are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
01
Miami, Florida, 33136, United States
-
02
Miami, Florida, 33146, United States
-
03
Orlando, Florida, 32809, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple scan and blood test outsmart liver cancer?
- A new procedure may offer relief for Cirrhosis-Related fluid buildup
- Liver health and drug processing: a closer look at casdatifan
- Can liver damage predict how drugs behave?
- Better crystal ball for liver crisis: new scores put to the test
- Blood thinner may stop early cirrhosis from turning deadly — a major trial puts it to the test