Liver function may change how itch drug works in body

NCT ID NCT04020016

First seen Apr 06, 2026 · Last updated May 08, 2026 · Updated 2 times

Summary

This early-phase study looked at how the drug nalbuphine extended-release is processed in people with mild, moderate, or severe liver problems compared to those with healthy livers. It also explored whether the drug could help relieve itching in participants who reported it. The study involved 28 adults and focused on safety and drug levels in the blood.

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Contacts and locations

Locations

  • 01

    Miami, Florida, 33136, United States

  • 02

    Miami, Florida, 33146, United States

  • 03

    Orlando, Florida, 32809, United States

Conditions

Explore the condition pages connected to this study.