Can a common supplement help you quit both tobacco and weed?
NCT ID NCT04627922
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study tested whether N-acetylcysteine (NAC), an over-the-counter supplement, can help people who use both tobacco and cannabis quit both substances. Fifty-nine regular smokers who also used cannabis took either NAC or a placebo for 8 weeks. Researchers tracked how often they used each substance and checked for abstinence using saliva tests.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-acetylcysteine (NAC)
- What this could lead to
- If it works, this could point toward a treatment for people who want to quit both tobacco and cannabis.
- What could go wrong
- This is a small, early-phase trial with only 59 participants. The supplement may not work better than a placebo, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
San Francisco Veterans Affairs Medical Center
San Francisco, California, 94121, United States
More trials for these conditions
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