Brain scans may predict memory problems after radiation for brain tumors

NCT ID NCT04073966

Recruiting now Knowledge-focused Sponsor: UNC Lineberger Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study uses special MRI scans to see how radiation treatment affects the brain's white matter and thinking skills in people with cancer that has spread to the brain. Researchers will follow 15 patients to find early signs of memory or concentration problems. The goal is to better understand these side effects so doctors can reduce them in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors predict and reduce memory and thinking problems after brain radiation.
What could go wrong: This is a very small pilot study with only 15 participants, so results may not apply to everyone. It is observational, meaning it does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRAIN METASTASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain cancer Leukoaraiosis metastatic malignant neoplasm in the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN METASTASES NEUROCOGNITIVE DEFICIT RADIATION EXPOSURE WHITE MATTER ALTERATIONS

Contacts and locations

Locations

University of North Carolina at Chapel Hill, Department of Radiation Oncology
RECRUITING

Chapel Hill, North Carolina, 27599, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.