Can we map a Tumor's genes fast enough to help patients?

NCT ID NCT03546127

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether advanced genetic sequencing of tumors can be done quickly enough to guide treatment decisions. Researchers took blood and tumor samples from 24 adults with advanced soft-tissue sarcoma or metastatic colorectal cancer. They measured how long it took to get a complete genetic report back to the doctor. The goal was to see if this process is practical in a real-world hospital setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Next Generation Sequencing (genetic testing of tumor and blood samples)
What this could lead to: If successful, this could show that routine genetic profiling of tumors is feasible within a useful timeframe, potentially helping doctors choose more personalized treatments for cancer patients.
What could go wrong: This is a very small pilot study (24 patients) focused only on feasibility and timing, not on whether profiling actually improves patient outcomes. It may not lead to direct treatment benefits.

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Conditions

The condition(s) this trial relates to.

colorectal carcinoma colorectal neoplasm sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CARCINOMA SOFT TISSUE SARCOMA

Contacts and locations

Locations

CEA / Centre National de Recherche en Génomique Humaine

Évry, 91057, France
Hôpital Européen Georges Pompidou

Paris, 75000, France
Institut Bergonié

Bordeaux, 33076, France

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