Could a Mitochondria-Targeting pill ease asthma in obesity?

NCT ID NCT04026711

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 trial tested whether MitoQ, a drug that targets cell energy centers, can improve airway reactivity in 47 obese adults with poorly controlled asthma. Participants took MitoQ or a placebo daily for 12 weeks. The study aimed to see if MitoQ could help control asthma symptoms in this specific group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MitoQ (mitoquinol)

What this could lead to

If it works, MitoQ could offer a new way to improve asthma control in people with obesity by targeting metabolic dysfunction.

What could go wrong

This is a small, early-phase pilot study with only 47 participants. Results may not apply to all asthma patients, and the treatment may not show significant benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University

    Durham, North Carolina, 27710, United States

  • University of Vermont

    Burlington, Vermont, 05405, United States