Can a common drug make fibroid surgery safer?
NCT ID NCT06882824
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether taking misoprostol before myomectomy (surgery to remove uterine fibroids) can reduce blood loss during the operation. 80 women aged 18-43 with symptomatic fibroids will receive either misoprostol or a placebo before surgery. The goal is to see if this simple, well-tolerated drug can lower the risk of heavy bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- misoprostol
- What this could lead to
- If it works, this could provide a simple, well-tolerated drug to reduce bleeding during fibroid surgery, making the procedure safer.
- What could go wrong
- This is a small, early-stage trial (80 people) testing a drug already used for other purposes. The benefit may be small or not statistically significant, and side effects like cramps or nausea are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Clermont-Ferrand
RECRUITINGClermont-Ferrand, Clermont-Ferrand, 63000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Fertility after fibroid embolization: new data from 46 women
- Which injection cuts bleeding best in fibroid surgery?
- New study aims to find safest method to cut blood loss in fibroid surgery
- Vitamin c IV may curb blood loss in hysterectomy