Which injection cuts bleeding best in fibroid surgery?

NCT ID NCT07390864

Recruiting now Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two drugs, ergometrine and carbetocin, injected into the uterus during fibroid removal surgery to see which reduces blood loss more. Forty women with symptomatic fibroids will be randomly assigned to receive one of the drugs. The goal is to find a better way to control bleeding and reduce the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Methylergometrine and Carbetocin (drugs injected into the uterus to reduce bleeding)
What this could lead to: If one drug proves better, it could become a standard way to reduce blood loss during fibroid surgery, lowering the need for transfusions.
What could go wrong: This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. Both drugs have side effects like nausea or changes in blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hemorrhage myofibroma uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOMA;UTERUS

Contacts and locations

Locations

Fayoum University
RECRUITING

Al Fayyum, Faiyum Governorate, 38521, Egypt

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