Which injection cuts bleeding best in fibroid surgery?

NCT ID NCT07390864

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two drugs, ergometrine and carbetocin, injected into the uterus during fibroid removal surgery to see which reduces blood loss more. Forty women with symptomatic fibroids will be randomly assigned to receive one of the drugs. The goal is to find a better way to control bleeding and reduce the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Methylergometrine and Carbetocin (drugs injected into the uterus to reduce bleeding)

What this could lead to

If one drug proves better, it could become a standard way to reduce blood loss during fibroid surgery, lowering the need for transfusions.

What could go wrong

This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. Both drugs have side effects like nausea or changes in blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hemorrhage myofibroma uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fayoum University

    RECRUITING

    Al Fayyum, Faiyum Governorate, 38521, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••