Swallow a sponge to detect esophageal cancer? new study investigates

NCT ID NCT03961945

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new, less invasive way to diagnose Barrett's esophagus and esophageal cancer using a sponge capsule that patients swallow. The sponge collects cells from the esophagus, which are then analyzed for signs of disease. Researchers will enroll 1,550 people aged 50-85 with risk factors like chronic acid reflux to see how accurate the sponge test is compared to standard endoscopy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus Barrett esophagus esophageal adenocarcinoma Esophageal Neoplasms gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Scott & White Research Institute

    COMPLETED

    Dallas, Texas, 75246, United States

  • Mayo Clinic Arizona

    COMPLETED

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic Health System-Eau Claire

    RECRUITING

    Eau Claire, Wisconsin, 54701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Health System-Franciscan Healthcare

    WITHDRAWN

    La Crosse, Wisconsin, 54601, United States

  • Mayo Clinic Health Systems - Austin

    RECRUITING

    Austin, Minnesota, 55912, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Health Systems - Mankato

    COMPLETED

    Mankato, Minnesota, 56001, United States

  • Mayo Clinic Jacksonville

    COMPLETED

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwell Health

    COMPLETED

    New Hyde Park, New York, 11040, United States