Gut bacteria may hold key to treating severe colitis
NCT ID NCT04272307
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether gut microorganisms and their byproducts play a role in triggering severe flare-ups of ulcerative colitis. Researchers will compare patients hospitalized with severe colitis to those with milder symptoms, analyzing stool and blood samples over three months. The goal is to find biological markers that could help doctors choose the most effective medical therapy and avoid the need for colon removal surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could identify biomarkers to guide personalized treatment for severe ulcerative colitis, potentially reducing the need for surgery.
What could go wrong
This is a small early-phase pilot study, so findings may not be definitive or generalizable. The research is observational and does not test a new treatment.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Hospitalier Universitaire de Bordeaux
Bordeaux, 33076, France