Could a diet change calm IBD by reshaping gut bacteria?

NCT ID NCT04757181

Completed Disease control Sponsor: University of Massachusetts, Worcester Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether a specific diet, called the IBD-AID, can improve symptoms of inflammatory bowel disease (IBD) by changing the bacteria in the gut. Participants aged 15 and older with IBD will follow the diet for 8 weeks, with guidance from study staff and cooking classes. Researchers will measure changes in gut microbes, inflammation in the blood, and symptom severity to see if the diet helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a dietary intervention called the IBD-AID (Inflammatory Bowel Disease Anti-Inflammatory Diet)
What this could lead to: If successful, this diet could offer a safe, drug-free way to manage IBD symptoms and improve quality of life.
What could go wrong: This is a small, early study without a control group, so results may not apply to everyone. Dietary changes can be hard to maintain, and the diet may not work for all types of IBD.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATORY BOWEL DISEASES

Contacts and locations

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Locations

University of Massachusetts Medical School

Worcester, Massachusetts, 01655, United States

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