Can a pill tame runaway cortisol? mayo clinic launches trial

NCT ID NCT06106295

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests whether the drug metyrapone is safe and effective for people with mild autonomous cortisol secretion (MACS), a condition where the body makes too much cortisol. About 30 adults will take the drug and be monitored for side effects. The goal is to see if metyrapone can help control the hormone imbalance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic Minnesota

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.