Researchers hunt for best test to spot hidden hormone problem in adrenal tumors

NCT ID NCT06344143

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 20 adults with adrenal tumors (incidentalomas) to find the most accurate tests for detecting mild autonomous cortisol secretion (MACS), a condition where the tumor releases extra cortisol. Participants will provide blood, saliva, and urine samples and undergo several stimulation tests. Researchers will track them for 4 years to see if their condition changes, aiming to improve diagnosis and understanding of this hormone imbalance.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••