One-Time drug may slash opioid use after hysterectomy

NCT ID NCT06536517

First seen Jan 05, 2026 · Last updated May 02, 2026 · Updated 27 times

Summary

This study tests whether giving a single dose of methadone during laparoscopic or robotic hysterectomy can lower the amount of opioid painkillers needed after surgery. The goal is to reduce opioid overprescription and the risk of abuse. About 100 adults having a hysterectomy for non-cancer reasons will take part. Half will get methadone during surgery, and the other half will get standard short-acting opioids.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Johns Hopkins Bayview Medical Center

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact

  • The Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

Conditions

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