Could Weight-Loss surgery tame a common heart rhythm disorder?
NCT ID NCT07027969
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether metabolic surgery (like gastric bypass) can reduce the severity of atrial fibrillation (AF), a common heart rhythm problem, in people with obesity. About 100 adults with AF and a BMI between 35 and 65 will be randomly assigned to either surgery or medication. The main goal is to see if surgery lowers the amount of time spent in AF over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metabolic surgery (Roux-en-Y gastric bypass or sleeve gastrectomy) or anti-obesity medication
What this could lead to
If successful, this could show that weight-loss surgery is an effective way to manage atrial fibrillation in people with obesity, potentially reducing symptoms and the need for other treatments.
What could go wrong
This is a small, early-phase trial with only 100 participants. Surgery carries risks like infection or complications, and the results may not apply to all patients with atrial fibrillation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Cleveland Clinic
Cleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••