Could Weight-Loss surgery tame a common heart rhythm disorder?
NCT ID NCT07027969
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether metabolic surgery (like gastric bypass) can reduce the severity of atrial fibrillation (AF), a common heart rhythm problem, in people with obesity. About 100 adults with AF and a BMI between 35 and 65 will be randomly assigned to either surgery or medication. The main goal is to see if surgery lowers the amount of time spent in AF over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metabolic surgery (Roux-en-Y gastric bypass or sleeve gastrectomy) or anti-obesity medication
- What this could lead to
- If successful, this could show that weight-loss surgery is an effective way to manage atrial fibrillation in people with obesity, potentially reducing symptoms and the need for other treatments.
- What could go wrong
- This is a small, early-phase trial with only 100 participants. Surgery carries risks like infection or complications, and the results may not apply to all patients with atrial fibrillation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Cleveland Clinic
Cleveland, Ohio, 44195, United States
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