Could hormone therapy cool hot flashes for women with HIV?

NCT ID NCT06856174

Recruiting now Symptom relief Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether hormone therapy (estrogen with or without progesterone) can safely reduce hot flashes and night sweats in women living with HIV. Researchers will also check if it improves sleep, mood, thinking, bone health, and quality of life. About 105 women aged 40 to 60 who are perimenopausal or early postmenopausal and on HIV treatment will take part.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTION MENOPAUSE

Contacts and locations

Locations

101 Massachusetts General Hospital (MGH) CRS
RECRUITING

Boston, Massachusetts, 02114, United States
201 Johns Hopkins University CRS
RECRUITING

Baltimore, Maryland, 21205, United States
2101 Washington University Therapeutics (WT) CRS
RECRUITING

St Louis, Missouri, 63110, United States
2401 Cincinnati CRS
RECRUITING

Cincinnati, Ohio, 45267-0405, United States
31788 Alabama CRS
RECRUITING

Birmingham, Alabama, 35294, United States
3201 Chapel Hill CRS
RECRUITING

Chapel Hill, North Carolina, 27516, United States
3203 Greensboro CRS
RECRUITING

Greensboro, North Carolina, 27401, United States
6201 Penn Therapeutics CRS
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
801 University of California, San Francisco HIV/AIDS CRS
RECRUITING

San Francisco, California, 94110, United States
Brigham and Women's Hosp. ACTG CRS (107)
RECRUITING

Boston, Massachusetts, 02115, United States
Case CRS (2501)
RECRUITING

Cleveland, Ohio, 44106, United States
Columbia Physicians and Surgeons (P&S) CRS (30329)
RECRUITING

New York, New York, 10032, United States
Harbor - UCLA Med. Ctr. CRS
RECRUITING

Torrance, California, 90502, United States
Houston AIDS Research Team CRS (31473)
RECRUITING

Houston, Texas, 77030, United States
New Jersey Medical School Clinical Research Center CRS (31786)
RECRUITING

Newark, New Jersey, 07103, United States
Northwestern University CRS (2701)
RECRUITING

Chicago, Illinois, 60611, United States
Ohio State University CRS (2301)
RECRUITING

Columbus, Ohio, 43210, United States
The Ponce de Leon Center CRS (5802)
RECRUITING

Atlanta, Georgia, 30308, United States
UCSD Antiviral Research Center CRS (701)
RECRUITING

San Diego, California, 92103, United States
Univ of Pittsburgh
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
University of California, Los Angeles CARE Center CRS (601)
RECRUITING

Los Angeles, California, 90035, United States
University of Colorado Hospital CRS (6101)
RECRUITING

Aurora, Colorado, 80045, United States
Weill Cornell Chelsea CRS (7804)
RECRUITING

New York, New York, 10010, United States

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