Could a sleep hormone tame bipolar mood swings?
NCT ID NCT07472075
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding melatonin (a natural sleep hormone) to standard treatment can help stabilize daily mood swings in people with bipolar disorder. Two hundred adults with bipolar disorder will take either a melatonin capsule or a placebo every day for six months. Their mood stability will be tracked using a smartphone app.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Melatonin
What this could lead to
If it works, this could point toward a simple, low-cost add-on treatment to help stabilize mood in bipolar disorder.
What could go wrong
This is a mid-stage trial with 200 participants, so results may not apply to everyone. Melatonin may not improve mood stability more than a placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mental Health Center Copenhagen, Copenhagen Affective Research Center (CADIC)
RECRUITINGFrederiksberg, 2000, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••