Can interferon keep melanoma from coming back after surgery?
NCT ID NCT07671495
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This completed phase 2 trial tested whether adding alpha interferon to standard surgery helps prevent skin melanoma from returning. 278 participants with stage I-IV melanoma were assigned to one of six groups, including surgery alone, low or high dose interferon, chemotherapy, or radiation. The study measured how long people lived without their cancer coming back and overall survival at 5 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- alpha interferon
- What this could lead to
- If successful, this could point toward a standard way to use alpha interferon after melanoma surgery to reduce the chance of the cancer coming back.
- What could go wrong
- This is a completed phase 2 trial, so results are not yet confirmed in larger studies. Interferon can cause side effects like flu-like symptoms and fatigue, and it may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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