Bone drug may supercharge immunotherapy against tough melanoma
NCT ID NCT03620019
First seen Mar 29, 2026 · Last updated Jun 13, 2026 · Updated 12 times
Summary
This study tested whether adding denosumab (a bone-strengthening drug) to standard immunotherapy (pembrolizumab or nivolumab) could help control advanced melanoma that has spread. Researchers enrolled 25 adults with stage III or IV melanoma who had not received prior immunotherapy. They measured changes in immune cells in blood and tumor samples to see if the combination boosted the body's attack on cancer.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dartmouth-Hitchcock Medical Center
Manchester, New Hampshire, 03104, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
Conditions
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