New drug could ease sleep apnea and help shed pounds

NCT ID NCT07225686

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new medicine, maridebart cafraglutide, for adults with obstructive sleep apnea who are overweight or obese and already use a CPAP machine. The goal is to see if the drug can reduce breathing pauses during sleep and help with weight loss over 52 weeks. About 250 participants will receive either the drug or a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY OBSTRUCTIVE SLEEP APNEA

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advanced Sleep Research
RECRUITING

Berlin, 10117, Germany
Aggarwal and Associates Ltd
RECRUITING

Brampton, Ontario, L6T 0G1, Canada
Basil Clinical
RECRUITING

Laurelton, New York, 11413, United States
CPQuali Pesquisa Clinica Ltda
RECRUITING

São Paulo, São Paulo, 01228-000, Brazil
CTI Clinical Research Center
RECRUITING

Cincinnati, Ohio, 45212, United States
CaRe Clinic
RECRUITING

Calgary, Alberta, T2N 4L7, Canada
Centre Hospitalier Universitaire d'Angers
RECRUITING

Angers, 49933, France
Centre Hospitalier Universitaire de Bordeaux - Hopital Pellegrin
RECRUITING

Bordeaux, 33000, France
Centre Hospitalier Universitaire de Grenoble - Hopital Nord Michallon
RECRUITING

Grenoble, 38043, France
Centre Hospitalier Universitaire de Montpellier - Hôpital Arnaud de Villeneuve
RECRUITING

Montpellier, 34090, France
Centro Medico Teknon
RECRUITING

Barcelona, Catalonia, 08022, Spain
Centro Paulista de Investigacao Clinica Cepic
RECRUITING

São Paulo, 04266-010, Brazil
Cerebrovaskularni poradna sro
RECRUITING

Ostrava - Poruba, 708 00, Czechia
Clinical Research Center Of Florida
RECRUITING

Pompano Beach, Florida, 33060, United States
Debreceni Egyetem Klinikai Kozpont
RECRUITING

Debrecen, 4032, Hungary
Destiny Research Center
RECRUITING

Palmetto Bay, Florida, 33157, United States
Diabeteszentrum Hamburg West
RECRUITING

Hamburg, 22607, Germany
Diex Recherche Trois Rivieres
RECRUITING

Trois-Rivières, Quebec, G9A 4P3, Canada
Epic Medical Research - DeSoto
RECRUITING

DeSoto, Texas, 75115, United States
Erzsebet Gondozohaz
RECRUITING

Gödöllő, 2100, Hungary
Fakultni nemocnice Brno
RECRUITING

Brno, 625 00, Czechia
Fukuoka University Hospital
RECRUITING

Fukuoka, Fukuoka, 814-0180, Japan
FutureSearch Trials of Neurology
RECRUITING

Austin, Texas, 78731, United States
Gokeikai Osaka Kaisei Hospital
RECRUITING

Osaka, Osaka, 532-0003, Japan
Goodsleep Clinic
RECRUITING

Minato-ku, Tokyo, 105-0012, Japan
Hospices Civils de Lyon - Centre Hospitalier Lyon Sud
RECRUITING

Pierre-Bénite, 69495, France
Hospital Medico Quirurgico San Rafael
RECRUITING

A Coruña, Galicia, 15006, Spain
Hospital Quiron Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo Hcfmusp
RECRUITING

São Paulo, São Paulo, 05403-900, Brazil
InnoDiab Forschung
RECRUITING

Essen, 45136, Germany
Instituto de Pesquisa Clinica de Campinas - Ipecc
RECRUITING

Campinas, São Paulo, 13060-080, Brazil
Kuwamizu Hospital
RECRUITING

Kumamoto, Kumamoto, 862-0954, Japan
Mazda Hospital of Mazda Motor Corporation
RECRUITING

Aki-gun, Hiroshima, 735-8585, Japan
Monash Medical Centre
RECRUITING

Clayton, Victoria, 3168, Australia
Monroe Biomedical Research
RECRUITING

Monroe, North Carolina, 28112, United States
Nakamura Clinic
RECRUITING

Urasoe-shi, Okinawa, 901-2132, Japan
Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
RECRUITING

Warsaw, 04-635, Poland
Nemocnice Rudolfa a Stefanie Benesov as
RECRUITING

Benesov U Prahy, 256 01, Czechia
NeuroTrials Research
RECRUITING

Atlanta, Georgia, 30328, United States
Northwest Clinical Research Center
RECRUITING

Bellevue, Washington, 98007, United States
Nucleo de Pesquisa do Rio Grande do Sul
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-170, Brazil
Peninsula Research Associates
RECRUITING

Rolling Hills Estates, California, 90274, United States
RESM ShinYokohama Sleep and Respiratory Medical Care Clinic
RECRUITING

Yokohama, Kanagawa, 222-0033, Japan
Red-Institut GmbH
RECRUITING

Oldenburg, 23758, Germany
Reformatus Pulmonologiai Centrum
RECRUITING

Törökbálint, 2045, Hungary
Royal Brisbane and Womens Hospital
RECRUITING

Herston, Queensland, 4006, Australia
Saiseikai Futsukaichi Hospital
RECRUITING

Chikushino-shi, Fukuoka, 818-8516, Japan
Siteworks - Zentrum fuer klinische Studien Hannover
RECRUITING

Hanover, 30449, Germany
Siteworks - Zentrum fuer klinische Studien Karlsruhe
RECRUITING

Karlsruhe, 76137, Germany
Sleep Therapy & Research Center
RECRUITING

San Antonio, Texas, 78229, United States
Sleep and Mental Clinic-Kitahiroshima
RECRUITING

Kitahiroshima-shi, Hokkaido, 061-1121, Japan
SomnoCenter Budapest Alvaszavar Kozpont
RECRUITING

Budapest, 1012, Hungary
SomnoCenter Szeged Alvaszavar Kozpont
RECRUITING

Szeged, 6720, Hungary
Teradan Clinical Trials
RECRUITING

Brandon, Florida, 33511, United States
Uniwersytecki Szpital Kliniczny w Bialymstoku
RECRUITING

Bialystok, 15-276, Poland
Valley Clinical Trials
RECRUITING

Northridge, California, 91325, United States
Wharton Medical Clinic
RECRUITING

Hamilton, Ontario, L8L 5G8, Canada
Woolcock Institute of Medical Research
RECRUITING

Macquarie Park, New South Wales, 2113, Australia