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Can a pinch of magnesium make nerve blocks last longer?

NCT ID NCT07798115

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests whether adding magnesium sulfate to a standard nerve block improves pain control after shoulder arthroscopy. About 84 adults having outpatient shoulder surgery will receive the nerve block with or without magnesium. Researchers will measure how long pain relief lasts and how much pain patients report over the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Magnesium sulfate added to a standard nerve block with bupivacaine
What this could lead to
If it works, adding magnesium to nerve blocks could become a simple way to improve pain relief after shoulder surgery and reduce the need for extra painkillers.
What could go wrong
This is a small, early-stage trial, and the benefit may be modest or not appear at all. Magnesium can cause side effects like low blood pressure or drowsiness, and results may not apply to other surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18-50 years * American Society of Anesthesiologists (ASA) physical status I-II. * Scheduled for elective outpatient shoulder arthroscopy. * Ability to understand the study protocol and use the NRS scale. Exclusion Criteria: * Refusal to participate. * Known allergy or hypersensitivity to local anesthetics or magnesium sulphate. * Coagulopathy or anticoagulant therapy contraindicating regional anesthesia. * Local infection at the block site. * Pre-existing peripheral neuropathy or neurologic deficit involving the operative limb. * Body mass index (BMI) \> 40 kg/m² (if desired for technical standardization). * Chronic opioid use or chronic pain syndrome affecting pain assessment. * Pregnancy or lactation. * Inability to communicate or complete postoperative assessments.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain Regional anesthesia Shoulder arthroscopy

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Assiut University Hospital

    Asyut, Egypt

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