AI alerts in medical records aim to curb opioid overdoses

NCT ID NCT06806163

Recruiting now Disease control Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether showing doctors a warning flag in electronic health records for patients at high risk of opioid overdose can lead to safer prescribing. About 1,350 adults who recently received an opioid prescription will be included. Doctors in some clinics will see a simple flag, while others will also get extra reminders (nudges) to prescribe naloxone or avoid risky combinations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: EHR-embedded risk flag and behavioral nudges
What this could lead to: If successful, this could give doctors a simple, data-driven tool to reduce opioid overdose risk through safer prescribing.
What could go wrong: This is a behavioral intervention, not a drug. Its impact depends on how clinicians respond, and it may not reduce actual overdose rates.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute opioid poisoning opiate dependence Opiate Overdose opioid abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID OVERDOSE OPIOID USE OPIOID-USE DISORDER OPIOIDS

Contacts and locations

Locations

University of Pittsburgh
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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