New Parkinson's drug enters first human safety trials

NCT ID NCT06809400

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing an experimental drug called LY4006896 in healthy volunteers and people with Parkinson's disease. The main goal is to check if the drug is safe and how the body processes it. Researchers will give single or multiple doses and watch for side effects. The study involves 127 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LY4006896 (an experimental drug given intravenously)
What this could lead to: If successful, this could point toward a new treatment option for Parkinson's disease by targeting the underlying disease process.
What could go wrong: This is a very early Phase 1 trial focused on safety, not effectiveness. The drug may not work or could have side effects. It will take many more years of testing before it might become available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

Aqualane Clinical Research
RECRUITING

Naples, Florida, 34105, United States
Charter Research
RECRUITING

Orlando, Florida, 32803, United States
Charter Research
RECRUITING

The Villages, Florida, 32162-2698, United States
Collaborative Neuroscience Network - CNS
RECRUITING

Los Alamitos, California, 90720, United States
Collaborative Neuroscience Network - CNS
RECRUITING

Los Alamitos, California, 90720, United States
Evergreen Health Research
NOT_YET_RECRUITING

Kirkland, Washington, 98034, United States
Inland Northwest Research
NOT_YET_RECRUITING

Spokane, Washington, 99202, United States
K2 Medical Research, LLC
COMPLETED

Maitland, Florida, 32751, United States
K2 Medical Research, LLC
RECRUITING

The Villages, Florida, 32159, United States
Oita University Hospital
RECRUITING

Yufu, 879-5593, Japan
P-One Clinic
RECRUITING

Hachiōji, 192-0071, Japan
PPD Development, LP
RECRUITING

Austin, Texas, 78744, United States
Progressive Medical Research
RECRUITING

Port Orange, Florida, 32127, United States
QUEST Research Institute
RECRUITING

Farmington Hills, Michigan, 48334, United States

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