Sound waves could ease Parkinson's tremors without drugs

NCT ID NCT04593875

Completed Symptom relief Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether low-intensity focused ultrasound (LIFUP) can safely improve motor symptoms like tremor and stiffness in people with Parkinson's disease. 31 participants received either real or sham ultrasound to a specific brain area. The goal was to see if this non-invasive technique could boost brain activity and improve movement, potentially offering a new drug-free option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low-intensity focused ultrasound (LIFUP) device
What this could lead to: If successful, this could lead to a non-invasive, non-drug treatment to help improve movement problems in Parkinson's disease.
What could go wrong: This was a small, early feasibility study with only 31 people. It is not yet proven to work, and more research is needed to confirm any benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

University of California, Los Angeles

Los Angeles, California, 90095, United States

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Other studies related to the condition(s) this trial covers.