Gene therapy for Parkinson's: will it last? new study tracks 6 patients over time

NCT ID NCT07629115

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 4 times

Summary

This study checks the long-term safety and lasting effects of a gene therapy called IPS101A in 6 people with severe Parkinson's disease who already received it in an earlier trial. Researchers will monitor side effects and measure changes in movement symptoms over time. The goal is to see if a one-time gene therapy can safely control Parkinson's for years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
IPS101A gene therapy
What this could lead to
If successful, this could show that a single dose of gene therapy safely controls Parkinson's symptoms for years, reducing the need for daily medications.
What could go wrong
This is a very small follow-up study with only 6 people, so results may not apply to everyone. It is also early-stage, so long-term risks or loss of effect are still unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Severance Hospital

    RECRUITING

    Seoul, South Korea

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