New hope for hypothalamic obesity: Long-Term drug trial launches

NCT ID NCT07156578

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at the long-term safety and effects of a drug called bivamelagon in people with hypothalamic obesity, a condition where the brain's hunger control is damaged. About 25 participants who completed a previous study will take the drug for up to 2 years. Researchers will track side effects and changes in weight and body mass index.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired hypothalamic obesity Sexual Infantilism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Birmingham Women's and Children's NHS Foundation Trust

    Birmingham, B15 2TG, United Kingdom

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Columbia University

    New York, New York, 10027, United States

  • Great Ormond Street Hospital for Children

    London, WC1N 3JH, United Kingdom

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • The University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27514, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of Cambridge

    Cambridge, CB2 1TN, United Kingdom

  • University of Iowa Children's Hospital

    Iowa City, Iowa, 52242, United States