Acquired hypothalamic obesity
MONDO:09759227 clinical trials for this condition and its sub-types, 7 tagged with Acquired hypothalamic obesity itself.
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Hope for hypothalamic obesity: daily shot targets weight and hunger
Disease control Recruiting nowThis phase 3 trial tests whether a daily injection of setmelanotide can help people aged 4 and older with hypothalamic obesity lose weight and feel less hungry. Participants will receive either the drug or a placebo for 26 weeks. The study aims to see if the treatment leads to me…
Phase 3 • Sponsor: Rhythm Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New weekly shot aims to curb obesity in rare genetic disorders
Disease control Recruiting nowThis study tests a weekly injection called RM-718 in healthy people with obesity and in patients with obesity caused by problems in the MC4R pathway, including hypothalamic obesity and Prader-Willi syndrome. The main goal is to check the drug's safety and how the body processes i…
Phase 1/2 • Sponsor: Rhythm Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Could a diabetes drug help teens with rare obesity syndromes shed pounds?
Disease control Recruiting nowThis study tests tirzepatide, a weight loss medication, in 36 young adults aged 18-26 with obesity from Prader-Willi syndrome, hypothalamic obesity, or general causes. Participants take the drug for 48 weeks to see how much weight they lose and how their health changes. The goal …
Phase 4 • Sponsor: Grace Kim • Aim: Disease control
Last updated Jun 26, 2026 17:35 UTC