Could a diabetes drug help teens with rare obesity syndromes shed pounds?
NCT ID NCT06901245
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests tirzepatide, a weight loss medication, in 36 young adults aged 18-26 with obesity from Prader-Willi syndrome, hypothalamic obesity, or general causes. Participants take the drug for 48 weeks to see how much weight they lose and how their health changes. The goal is to find if tirzepatide works as well for genetic or brain-injury-related obesity as it does for common obesity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tirzepatide
What this could lead to
If it works, this could point toward a weight management option for young adults with hard-to-treat obesity due to genetic or brain injury causes.
What could go wrong
This is a small, early-phase study with only 36 participants, so results may not apply widely. Tirzepatide may cause side effects like nausea or vomiting, and weight loss may not be sustained long-term.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Minnesota
RECRUITINGSaint Paul, Minnesota, 55102, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37203, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••