HYPOTHALAMIC OBESITY
Clinical trials for HYPOTHALAMIC OBESITY explained in plain language.
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Promising drug targets severe weight gain from brain damage
Disease control Recruiting nowThis study tests a daily injection called setmelanotide to help people aged 4 and older who have severe obesity due to a brain condition (hypothalamic obesity). Participants receive either the drug or a placebo for 26 weeks. The goal is to see if it reduces weight, hunger, and im…
Matched conditions: HYPOTHALAMIC OBESITY
Phase: PHASE3 • Sponsor: Rhythm Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 17, 2026 04:13 UTC
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Could a diabetes drug help young adults with rare obesity conditions lose weight?
Disease control Recruiting nowThis study is testing a weight-loss medication called tirzepatide in young adults aged 18-26 who have obesity due to Prader-Willi syndrome, hypothalamic obesity, or general causes. Participants will take the drug for one year to see how much weight they lose and how their health …
Matched conditions: HYPOTHALAMIC OBESITY
Phase: PHASE4 • Sponsor: Grace Kim • Aim: Disease control
Last updated May 17, 2026 04:12 UTC
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New weekly shot hopes to tame genetic obesity
Disease control Recruiting nowThis study tests a new weekly injection called RM-718 in people with obesity, including those with a genetic condition affecting the MC4R pathway (like Prader-Willi syndrome). The main goal is to check the drug's safety and how the body processes it. About 150 participants will t…
Matched conditions: HYPOTHALAMIC OBESITY
Phase: PHASE1, PHASE2 • Sponsor: Rhythm Pharmaceuticals, Inc. • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC