New liver support protocol could help patients avoid transplant

NCT ID NCT07593638

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a treatment for adults with acute-on-chronic liver failure, a sudden worsening of long-term liver disease. The approach combines blood filtering (hemoadsorption) with half-dose plasma exchange to support the liver until recovery or transplant. About 240 participants will receive either this protocol or standard care, and researchers will track survival and need for liver transplant at 28 days.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Unidade Hospitalar de Bragança

    Bragança, Braganza District, 5301-852, Portugal

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