Stem cell injection aims to prevent deadly liver complication

NCT ID NCT07276568

ENROLLING_BY_INVITATION Disease control Sponsor: Zhi-Jun Zhu Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether injecting special liver-like cells into the abdominal muscle can help prevent or treat Small-for-Size syndrome, a serious complication that can occur after partial liver surgery. The study involves 12 patients and focuses mainly on safety, checking for side effects and changes in liver function. If the approach proves safe, it may pave the way for larger studies to see if it truly improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hepatocyte-like cells (derived from induced pluripotent stem cells)

What this could lead to

If successful, this could lead to a new way to prevent or treat Small-for-Size syndrome, a serious complication after liver surgery, potentially improving survival.

What could go wrong

This is a very early (Phase 1) trial with only 12 participants, so safety and effectiveness are not yet proven. There is a risk of injection-related side effects or the cells not working as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute liver failure chronic liver failure liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Province, 100050, China