Stem cell injection aims to prevent deadly liver complication

NCT ID NCT07276568

ENROLLING_BY_INVITATION Disease control Sponsor: Zhi-Jun Zhu Source: ClinicalTrials.gov โ†—

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tests whether injecting special liver-like cells into the abdominal muscle can help prevent or treat Small-for-Size syndrome, a serious complication that can occur after partial liver surgery. The study involves 12 patients and focuses mainly on safety, checking for side effects and changes in liver function. If the approach proves safe, it may pave the way for larger studies to see if it truly improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Hepatocyte-like cells (derived from induced pluripotent stem cells)
What this could lead to
If successful, this could lead to a new way to prevent or treat Small-for-Size syndrome, a serious complication after liver surgery, potentially improving survival.
What could go wrong
This is a very early (Phase 1) trial with only 12 participants, so safety and effectiveness are not yet proven. There is a risk of injection-related side effects or the cells not working as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Province, 100050, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.