New combo therapy targets liver tumors with precision

NCT ID NCT05286814

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This study tests whether adding an immune-boosting drug (PDS01ADC) to standard chemotherapy delivered directly to the liver can shrink tumors in people with certain cancers that have spread to the liver. About 70 adults with colorectal, bile duct, or adrenal cancer will receive the treatment through a surgically placed pump and regular IV chemo. The goal is to see if the combination works better than chemo alone.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.