Brain scans reveal Lithium's secret workings in bipolar depression

NCT ID NCT03336918

First seen Feb 26, 2026 · Last updated May 16, 2026 · Updated 8 times

Summary

This study looks at how lithium, a common treatment for bipolar disorder, changes the brain's wiring. Researchers will use MRI scans to track brain connections in 120 people with bipolar depression over 26 weeks. The goal is to understand why lithium works, not to test a new treatment.

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Contacts and locations

Locations

  • Cleveland Clinic Foundation Center for Behavioral Health

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.