New drug combo shows promise for Tough-to-Treat anal cancer

NCT ID NCT06669572

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining two drugs, lenvatinib and pembrolizumab, can shrink or control advanced anal or rectal cancer that has spread and stopped responding to standard chemotherapy. About 35 adults with this type of cancer will receive the drug combination. The goal is to see how many patients experience tumor shrinkage or disease stabilization.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma rectal cancer squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Medicine Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact