New study aims to spare oral cancer patients from unnecessary neck surgery

NCT ID NCT02743832

Recruiting now Knowledge-focused Sponsor: Jinsong Hou Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a feature called tumor budding can help doctors decide if early-stage oral cancer patients need neck lymph node removal. About 524 participants will be randomly assigned to either have the main tumor removed alone or also have neck dissection. The goal is to see if skipping neck dissection is safe and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors decide which early-stage oral cancer patients need neck surgery, reducing unnecessary procedures.
What could go wrong: This is an observational study without a new drug or treatment, so it won't directly cure or control the disease. Results may not change standard care immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARCINOMA, SQUAMOUS CELL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

oral cavity squamous cell carcinoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, SQUAMOUS CELL

Contacts and locations

Locations

Guanghua School of Stomatolagy, Hospital of Stomatology Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, 510055, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.