New study aims to spare oral cancer patients from unnecessary neck surgery

NCT ID NCT02743832

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a feature called tumor budding can help doctors decide if early-stage oral cancer patients need neck lymph node removal. About 524 participants will be randomly assigned to either have the main tumor removed alone or also have neck dissection. The goal is to see if skipping neck dissection is safe and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors decide which early-stage oral cancer patients need neck surgery, reducing unnecessary procedures.

What could go wrong

This is an observational study without a new drug or treatment, so it won't directly cure or control the disease. Results may not change standard care immediately.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARCINOMA, SQUAMOUS CELL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

oral cavity squamous cell carcinoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guanghua School of Stomatolagy, Hospital of Stomatology Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510055, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••