Experimental drug aims to supercharge immune system before cancer surgery

NCT ID NCT03336606

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tested a single dose of an experimental antibody (MEDI0562) given before surgery to 13 patients with advanced head and neck cancer or melanoma. The goal was to see if the drug safely activates the immune system to fight the cancer. Researchers compared giving the dose all at once versus splitting it over three days.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma melanoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck squamous cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States