Smoking and drinking leave genetic marks in mouth cells that may lead to cancer

NCT ID NCT06094829

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 100 healthy adults to see how tobacco and alcohol use cause genetic changes in cells lining the mouth. Researchers collected cheek cells using a gentle brush and searched for mutations linked to oral cancer. The goal was to understand how these substances might drive early cancer development, but the study does not provide any direct diagnosis or treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify early genetic changes linked to oral cancer, potentially improving future screening or prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It cannot diagnose cancer or predict individual risk, and results may not lead to immediate clinical changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cabinet Libéral Balayre

    Chassieu, 69680, France

  • Cabinet Libéral Bondil

    Villefranche-sur-Saône, 69400, France

  • Cabinet Libéral Calvo

    Quint-Fonsegrives, 31130, France

  • Cabinet Libéral Cougot

    Meudon, 92190, France

  • Cabinet Libéral Debeauvais

    Châtillon-Coligny, 45230, France

  • Cabinet Libéral Dutour

    Theix, 63122, France

  • Cabinet Libéral Finet

    Fontaine-lès-Dijon, 21121, France

  • Cabinet Libéral Glomet

    Saumur, 49400, France

  • Cabinet Libéral Grammatica

    Lyon, 69008, France

  • Cabinet Libéral Jaeggy

    Haguenau, 67500, France

  • Cabinet Libéral Janisset-Masse

    Villiers-sur-Marne, 95350, France

  • Cabinet Libéral Masri

    Vandœuvre-lès-Nancy, 54500, France

  • Cabinet Libéral Picquendar

    Bougival, 78380, France

  • Centre de Consultations et de Traitements Dentaires HCL

    Lyon, 69007, France

  • Unité de chirurgie et médecine orales (UCMO) - HCL - Hôpital Edouard Herriot- Pavillon R

    Lyon, 69003, France