Muscle-Saving combo tested alongside popular Weight-Loss meds

NCT ID NCT06885736

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether resistance exercise and extra protein can help preserve muscle mass in people starting weight-loss drugs like semaglutide or tirzepatide. 232 adults with obesity will be randomly assigned to one of four groups: control, extra protein, exercise, or both. The goal is to see if these strategies prevent muscle loss and improve physical function over 6 months.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
resistance exercise and increased protein intake
What this could lead to
If it works, this could show a way to prevent muscle loss while taking weight-loss drugs, leading to healthier weight loss.
What could go wrong
This is a relatively small, early-stage study without a drug approval phase. Results may not apply to everyone, and sticking to exercise and diet changes can be hard.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dasman Diabetes Institute

    RECRUITING

    Kuwait City, Kuwait

More trials for these conditions

Other studies related to the condition(s) this trial covers.