Muscle-Saving combo tested alongside popular Weight-Loss meds
NCT ID NCT06885736
First seen Mar 28, 2026 · Last updated Jun 22, 2026 · Updated 12 times
Summary
This study tests whether resistance exercise and extra protein can help preserve muscle mass in people starting weight-loss drugs like semaglutide or tirzepatide. 232 adults with obesity will be randomly assigned to one of four groups: control, extra protein, exercise, or both. The goal is to see if these strategies prevent muscle loss and improve physical function over 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dasman Diabetes Institute
RECRUITINGKuwait City, Kuwait
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
resistance exercise and increased protein intake
What this could lead to
If it works, this could show a way to prevent muscle loss while taking weight-loss drugs, leading to healthier weight loss.
What could go wrong
This is a relatively small, early-stage study without a drug approval phase. Results may not apply to everyone, and sticking to exercise and diet changes can be hard.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.