Zapping stubborn cancer spots may extend life of current drug therapy

NCT ID NCT06101290

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether adding targeted radiation or heat-based ablation to ongoing drug therapy can control genitourinary cancers (prostate, bladder, or kidney) that have started growing in only a few new areas. Participants continue their current systemic treatment while receiving stereotactic body radiation or interventional ablation to the progressing tumors. The goal is to see if this combination delays the need to switch or stop systemic therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic ablative radiotherapy (SABR) or interventional radiology (IR) ablation therapy

What this could lead to

If successful, this approach could help people with certain genitourinary cancers delay changing or stopping their systemic therapy by treating limited tumor growth with targeted local treatment.

What could go wrong

This is a mid-stage trial with 150 participants, so results may not apply to everyone. Local ablative therapy carries risks of side effects like pain, infection, or damage to nearby organs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer renal cell carcinoma transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Davis

    RECRUITING

    Sacramento, California, 95817, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••